Post by beebs on Sept 22, 2012 14:54:54 GMT -5
Published studies show Benfotiamine helpful to
restoring endothelial function, and those
suffering from diabetes, hypoglycemia, ensuing
kidney failure, and vision. Note lack of can cause
depression, heart arrythymia, insomnia etc.
"Food sources of Vitamin B6: whole grain products, whole rice, wheat germ, brewer’s yeast, egg yolk, peanuts, bananas, sunflower seeds. The special, fat-soluble, food-form of B1 called benfotiamine is only obtained from crushed garlic, onions, leeks and shallots."www.mwt.net/~drbrewer/benfotiamine.htm
1. Diglas J, Willinger C, Neu U, Irsigler K. Morbidity and mortality in type 1 and type 2 diabetes mellitus after the diagnosis of diabetic retinopathy. Dtsch Med Wochenschr. 1992 Nov 6;117(45):1703-8.
2. Stracke H, Hammes HP, Werkmann D, et al. Efficacy of benfotiamine versus thiamine on function and glycation products of peripheral nerves in diabetic rats. Exp Clin Endocrinol Diabetes. 2001;109(6):330-6.
3. Haupt E, Ledermann H, Kopcke W. Benfotiamine in the treatment of diabetic polyneuropathy—a three-week randomized, controlled pilot study (BEDIP study). Int J Clin Pharmacol Ther. 2005 Feb;43(2):71-7.
4. Sanchez-Ramirez GM, Caram-Salas NL, Rocha-Gonzalez HI, et al. Benfotiamine relieves inflammatory and neuropathic pain in rats. Eur J Pharmacol. 2006 Jan 13;530(1-2):48-53.
5. Babaei-Jadidi R, Karachalias N, Ahmed N, Battah S, Thornalley PJ. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes. 2003 Aug;52(8):2110-20.
6. Woelk H, Lehrl S, Bitsch R, Kopcke W. Benfotiamine in treatment of alcoholic polyneuropathy: an 8-week randomized controlled study (BAP I Study). Alcohol Alcohol. 1998 Nov;33(6):631-8.
7. Winkler G, Pal B, Nagybeganyi E, et al. Effectiveness of different benfotiamine dosage regimens in the treatment of painful diabetic neuropathy. Arzneimittelforschung. 1999 Mar;49(3):220-4.
8. Hammes HP, Du X, Edelstein D, et al. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nat Med. 2003 Mar;9(3):294-9.
9. Arora S, Lidor A, Abularrage CJ, et al. Thiamine (vitamin B(1)) improves endothelium-dependent vasodilatation in the presence of hyperglycemia. Ann Vasc Surg. 2006 May 31.
10. [No authors listed]. Benfotiamine.Monograph. Altern Med Rev. 2006;11(3):238-42.
11. Pomero F, Molinar MA, La SM, et al. Benfotiamine is similar to thiamine in correcting endothelial cell defects induced by high glucose. Acta Diabetol. 2001;38(3):135-8.
12. Bitsch R, Wolf M, Moller J, Heuzeroth L, Gruneklee D. Bioavailability assessment of the lipophilic benfotiamine as compared to a water-soluble thiamin derivative. Ann Nutr Metab. 1991;35(5):292-6.
13. Beltramo E, Berrone E, Buttiglieri S, Porta M. Thiamine and benfotiamine prevent increased apoptosis in endothelial cells and pericytes cultured in high glucose. Diabetes Metab Res Rev. 2004 Jul;20(4):330-6.
14. Thomas MC, Baynes JW, Thorpe SR, Cooper ME. The role of AGEs and AGE inhibitors in diabetic cardiovascular disease. Curr Drug Targets. 2005 Jun;6(4):453-74.
15. Cameron NE, Gibson TM, Nangle MR, Cotter MA. Inhibitors of advanced glycation end product formation and neurovascular dysfunction in experimental diabetes. Ann NY Acad Sci. 2005 Jun;1043:784-92.
16. Sheehan P. Peripheral arterial disease in people with diabetes: consensus statement recommends screening. Clinical Diabetes. 2004:22:179-80.
17. Li SY, Du M, Dolence EK, et al. Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging Cell. 2005 Apr;4(2):57-64.
18. Sadekov RA, Danilov AB, Vein AM. Diabetic polyneuropathy treatment by milgamma-100 preparation. Zh Nevrol Psikhiatr Im SS Korsakova. 1998;98(9):30-2.
19. Kolomoiskaia MB, Degonskii AI, Grishina RA. The myocardial contractile function and central hemodynamics of patients with insulin-dependent diabetes mellitus during treatment. Probl Endokrinol (Mosk). 1989 Jul;35(4):12-5.
20. Wu S, Ren J. Benfotiamine alleviates diabetes-induced cerebral oxidative damage independent of advanced glycation end-product, tissue factor and TNF-alpha. Neurosci Lett. 2006 Feb 13;394(2):158-62.
21. Available at: www.diabetesselfmanagement.com/article.cfm?aid=558. Accessed October 23, 2006.
22. Stirban A, Negrean M, Stratmann B, et al. Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes Care. 2006 Sep;29(9):2064-71.
23. Marchetti V, Menghini R, Rizza S, et al. Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling. Diabetes. 2006 Aug;55(8):2231-7.
24. Gadau S, Emanueli C, Van LS, et al. Benfotiamine accelerates the healing of ischaemic diabetic limbs in mice through protein kinase B/Akt-mediated potentiation of angiogenesis and inhibition of apoptosis. Diabetologia. 2006 Feb;49(2):405-20.
25. Sanada H, Higashi Y, Goto C, Chayama K, Yoshizumi M, Sueda T. Vascular function in patients with lower extremity peripheral arterial disease: a comparison of functions in upper and lower extremities. Atherosclerosis. 2005 Jan;178(1):179-85.
26. Fadini GP, Miorin M, Facco M, et al. Circulating endothelial progenitor cells are reduced in peripheral vascular complications of type 2 diabetes mellitus. J Am Coll Cardiol. 2005 May 3;45(9):1449-57.
27. Ceylan-Isik AF, Wu S, Li Q, Li SY, Ren J. High-dose benfotiamine rescues cardiomyocyte contractile dysfunction in streptozotocin-induced diabetes mellitus. J Appl Physiol. 2006 Jan;100(1):150-6.
28. Lonsdale D. A review of the biochemistry, metabolism and clinical benefits of thiamin(e) and its derivatives. Evid Based Complement Alternat Med. 2006 Mar;3(1):49-59.