Post by beebs on Sept 11, 2012 15:41:13 GMT -5
A recent article, discussed statins. It pushes plaques further in cells,
depletes of COQ 10, causes damage
to mitochondria=inflammation. This study included Diabetes
Type 2, who are probably on insulin, which is a major cause
of cardiovascular disease.
Slightly elevated cholesterol is protective, counteracts infllammation and is not as unhealthy since changing reference range for profit.
Recent studies show
those who have lower cholesterol are more at risk or
strokes and heart attacks. Check it out on PubMed.
Much healthier way to keep cholesterol within normal range,
by eating mustard leaves, curry leaves, and other food source.
and intensive nutritional therapy. It depends on the trigger, which could also be hypothyroidism,
metabolic disorders and more, which needs to be addressed.
Diabetes Care. 2012 Aug 8. [Epub ahead of print]
Progression of Vascular Calcification Is Increased With Statin Use in the Veterans Affairs Diabetes Trial (VADT).
Saremi A, Bahn G, Reaven PD; for the VADT Investigators.
Source
Phoenix VA Health Care System, Phoenix, Arizona.
Abstract
OBJECTIVETo determine the effect of statin use on progression of vascular calcification in type 2 diabetes (T2DM).RESEARCH DESIGN AND METHODSProgression of coronary artery calcification (CAC) and abdominal aortic artery calcification (AAC) was assessed according to the frequency of statin use in 197 participants with T2DM.\
RESULTS
After adjustment for baseline CAC and other confounders, progression of CAC was significantly higher in more frequent statin users than in less frequent users (mean ± SE, 8.2 ± 0.5 mm(3) vs. 4.2 ± 1.1 mm(3); P < 0.01). AAC progression was in general not significantly increased with more frequent statin use; in a subgroup of participants initially not receiving statins, however, progression of both CAC and AAC was significantly increased in frequent statin users.
CONCLUSION
More frequent statin use is associated with accelerated coronary artery calcification in T2DM patients with advanced atherosclerosis.
www.ncbi.nlm.nih.gov/pubmed?term=%5Bi%5D%20Aramesh%20Saremi%2C%20Gideon%20Bahn%2C%20Peter%20D%20Reaven%2C%20Progression%20of%20Vascular%20Calcification%20Is%20Increased%20With%20Statin%20Use%20in%20the%20Veterans%20Affairs%20Diabetes%20Trial%20(VADT).%20Diabetes%20Care.%202012%20Aug%208.%20Epub%202012%20Aug%208.%20PMID%3A%2022875226
depletes of COQ 10, causes damage
to mitochondria=inflammation. This study included Diabetes
Type 2, who are probably on insulin, which is a major cause
of cardiovascular disease.
Slightly elevated cholesterol is protective, counteracts infllammation and is not as unhealthy since changing reference range for profit.
Recent studies show
those who have lower cholesterol are more at risk or
strokes and heart attacks. Check it out on PubMed.
Much healthier way to keep cholesterol within normal range,
by eating mustard leaves, curry leaves, and other food source.
and intensive nutritional therapy. It depends on the trigger, which could also be hypothyroidism,
metabolic disorders and more, which needs to be addressed.
Diabetes Care. 2012 Aug 8. [Epub ahead of print]
Progression of Vascular Calcification Is Increased With Statin Use in the Veterans Affairs Diabetes Trial (VADT).
Saremi A, Bahn G, Reaven PD; for the VADT Investigators.
Source
Phoenix VA Health Care System, Phoenix, Arizona.
Abstract
OBJECTIVETo determine the effect of statin use on progression of vascular calcification in type 2 diabetes (T2DM).RESEARCH DESIGN AND METHODSProgression of coronary artery calcification (CAC) and abdominal aortic artery calcification (AAC) was assessed according to the frequency of statin use in 197 participants with T2DM.\
RESULTS
After adjustment for baseline CAC and other confounders, progression of CAC was significantly higher in more frequent statin users than in less frequent users (mean ± SE, 8.2 ± 0.5 mm(3) vs. 4.2 ± 1.1 mm(3); P < 0.01). AAC progression was in general not significantly increased with more frequent statin use; in a subgroup of participants initially not receiving statins, however, progression of both CAC and AAC was significantly increased in frequent statin users.
CONCLUSION
More frequent statin use is associated with accelerated coronary artery calcification in T2DM patients with advanced atherosclerosis.
www.ncbi.nlm.nih.gov/pubmed?term=%5Bi%5D%20Aramesh%20Saremi%2C%20Gideon%20Bahn%2C%20Peter%20D%20Reaven%2C%20Progression%20of%20Vascular%20Calcification%20Is%20Increased%20With%20Statin%20Use%20in%20the%20Veterans%20Affairs%20Diabetes%20Trial%20(VADT).%20Diabetes%20Care.%202012%20Aug%208.%20Epub%202012%20Aug%208.%20PMID%3A%2022875226